alk4 ca cat 27223 dna plasmids (Addgene inc)
Structured Review

Alk4 Ca Cat 27223 Dna Plasmids, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/alk4+ca+cat+27223+dna+plasmids/bio_rxiv__64898__2025__12__13__694153-310-6-15?v=Addgene+inc
Average 93 stars, based on 2 article reviews
Images
1) Product Images from "A Model for the Diversity Explosion Fundamental to Metastasis"
Article Title: A Model for the Diversity Explosion Fundamental to Metastasis
Journal: bioRxiv
doi: 10.64898/2025.12.13.694153
Figure Legend Snippet: Chromosome squashes of ALK4 KO cells showing examples of fluorescently labeled (DAPI) chromosomes prepared after blockage in metaphase. The histograms show the number of times a particular number of chromosome pairs were found (n-77). The same data is binned as 5 (B) or 1 (C) chromosome/cell.
Techniques Used: Labeling
Figure Legend Snippet: When entering mitosis cells have maximum volumes, have rounded up, slightly detached from the substrate and therefore can be modeled as spherical. Cells cultures of equal confluence (60-80%) were imaged at 4 min intervals for 24 hr. Videos of cell cultures were observed both in forward and reverse to determine the last frame before cytokinesis. The diameter of each was then measured using ImageJ and volumes calculated as 4/3p(d/2) 3 . Consistent with the distributions of nuclear sizes, we find that the KO cell population were skewed toward the very small. Both normally passaged KO cultures and those regrown from cells gently rocked off from that culture showed very similar distributions. N=50 (EV), 144 (ALK4 KO), 86 (Rocked Off). A-C: Data plotted for individual cultures, D: Same data plotted together.
Techniques Used: